广西美登木化学成分研究

黄园园, 马国需, 杨峻山, 许旭东, 袁经权

中国药学杂志 ›› 2021, Vol. 56 ›› Issue (6) : 457-461.

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中国药学杂志 ›› 2021, Vol. 56 ›› Issue (6) : 457-461. DOI: 10.11669/cpj.2021.06.005
论著

广西美登木化学成分研究

  • 黄园园1, 马国需2, 杨峻山2, 许旭东2*, 袁经权3*
作者信息 +

Chemical Constituents of Maytenus guangxiensis

  • HUANG Yuan-yuan1, MA Guo-xu2, YANG Jun-shan2, XU Xu-dong2*, YUAN Jing-quan3*
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摘要

目的 研究广西美登木(Maytenus guangxiensis)的化学成分。方法 采用各种柱色谱及高效液相制备色谱相结合的方法进行分离纯化,根据理化性质及波谱数据确定化合物的结构。结果 从广西美登木的体积分数95%乙醇提取物中分离得到13个化合物,分别鉴定为2-呋喃甲酸(1)、(+)-erythro-7-O-ethylguaiacylglycerol(2)、吐叶醇(3)、5-甲氧基愈创木基丙三醇(4)、1, 2-bis(4-hydroxy-3-methoxyphenyl)-1, 3-propanediol(5)、耳草醇 A(6)、烟酰胺(7)、(1R, 2R)-1-(3, 4, 5-三甲氧基苯基)-1, 2, 3-丙三醇(8)、淫羊藿醇 A2(9)、(-)-lyoniresinol(10)、异落叶松树脂醇(11)、β-hydroxypropiovanillone(12)和楝叶吴萸素B(13)。结论 所有化合物均为首次从该属和该植物中分离得到。

Abstract

OBJECTIVE To study the chemical constituents from Maytenus guangxiensis. METHODS The constituents were isolated and purified by various column chromatographic techniques and high performance liquid chromatography(HPLC). The structures of the compounds were elucidated on the basis of their physicochemical properties and spectral data. RESULTS Thirteen compounds were isolated from the ethanol extract of Maytenus guangxiensis and identified as 2-furoic acid(1),(+)-erythro-7-O-ethylguaiacylglycerol(2), vomifoliol(3), 5-methoxyguaiacylglycerol(4), 1, 2-bis(4-hydroxy-3-methoxyphenyl)-1, 3-propanediol(5), hedyotisol A(6), nicotinamide(7),(1R, 2R)-1-(3, 4, 5-trimethoxyphenyl)-1, 2, 3-propanetriol(8), icariol A2(9),(-)-lyoniresinol(10), isolariciresinol(11), β-hydroxypropiovanillone(12), and evofolin B(13). CONCLUSION All compounds are isolated from Maytenus guangxiensis for the first time.

关键词

广西美登木 / 乙醇提取物 / 吐叶醇 / 耳草醇 A

Key words

Maytenus guangxiensis / ethanol extract / vomifoliol / hedyotisol A

引用本文

导出引用
黄园园, 马国需, 杨峻山, 许旭东, 袁经权. 广西美登木化学成分研究[J]. 中国药学杂志, 2021, 56(6): 457-461 https://doi.org/10.11669/cpj.2021.06.005
HUANG Yuan-yuan, MA Guo-xu, YANG Jun-shan, XU Xu-dong, YUAN Jing-quan. Chemical Constituents of Maytenus guangxiensis[J]. Chinese Pharmaceutical Journal, 2021, 56(6): 457-461 https://doi.org/10.11669/cpj.2021.06.005
中图分类号: R282   

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基金

瑶药创新体系建立及广西民族医药产业化技术平台建设项目资助(桂科能10100027-3)
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